Indole 3-carbinol has cancer-preventive effects, but it has not been shown to treat cancer in humans. Indole-3-carbinol, also called I3C, is a resulting compound that comes from eating vegetables such as Brussels sprouts, cabbage, cauliflower, broccoli, and kale.What is indole 3 carbinol (I3C)?
Although I3C is potent stuff, the problem is that to get these concentrations from the raw vegetables you would need to be eating two pounds a day of cabbage or broccoli. Much of the current research data for indole 3 carbinol is linked to the prevention and treatment of hormonally-driven cancers, like prostate and breast cancer.What are the side effects of indole-3-carbinol?
Bleeding conditions: Indole-3-carbinol might slow blood clotting. In theory, taking indole-3-carbinol might increase the risk of bleeding in people with bleeding disorders. Surgery: Indole-3-carbinol might slow blood clotting. In theory, taking indole-3-carbinol might cause bleeding complications during surgery.Does indole-3-carbinol tetrameric derivative induce G1 cell cycle arrest in breast cancer?
A new indole-3-carbinol tetrameric derivative inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines. Cancer Res. 2003;63:4028–4036.