Keyword Analysis & Research: indole 3 carbinol smell

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What is indole-3-carbinol?

Indole-3-carbinol is formed from a substance called glucobrassicin found in vegetables such as broccoli, Brussels sprouts, cabbage, collards, cauliflower, kale, mustard greens, turnips, and rutabagas. Indole-3-carbinol is formed when these vegetables are cut, chewed or cooked.

How does indole-3-carbinol interact with NEDD4?

In a second study Kundu et al. showed that in melanoma cells where PTEN is downregulated, indole-3-carbinol directly interacts with NEDD4 1 to prevent PTEN ubiquitination and subsequent proteasomal degradation. This results in stabilization of PTEN and inhibition of proliferation by downstream AKT signaling.

Is indindole-3-carbinol safe to take?

Indole-3-carbinol is POSSIBLY SAFE for most people when taken by mouth as a medicine under proper medical supervision. Doses up to 400 mg daily have been used safely for 3-76 months. It can cause side effects such as skin rashes and diarrhea.

Can indole-3-carbinol be used long term for papillomatosis?

Recurrent respiratory papillomatosis. There is some evidence that long-term use of indole-3-carbinol might reduce tumor (papilloma) growth in people with recurrent respiratory papillomatosis. Systemic lupus erythematosus (SLE).

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